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Symbol
Name
ID
Gpx1
glutathione peroxidase 1
MGI:104887
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Cerebral hemorrhage
Abnormal cerebral vascular morphology
Stroke
Ischemic stroke
Cerebral calcification
Calcification of falx cerebri
Abnormality of the nervous system
Spinal cord compression
Hemiplegia/hemiparesis
Postural instability
Paresthesia
Disease(s) Associated with GPX1
multiple myeloma
pseudoxanthoma elasticum
sickle cell anemia

Mouse Phenotypes
increased neuron apoptosis
cochlear inner hair cell degeneration
cochlear outer hair cell degeneration
increased susceptibility to ischemic brain injury
increased cerebral infarct size
cochlear ganglion degeneration
brain ischemia
Availability Mouse Genotype
Gpx1tm1Kola/Gpx1tm1Kola
Gpx1tm1Ysh/Gpx1tm1Ysh

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory